Biological Activities of Wild Sparassis crispa Extracts

New sesquiterpenoid from the mushroom Sparassis crispa.

A new sesquiterpenoid (1) was isolated from the mushroom, Sparassis crispa, along with a known sesquiterpenoid (2). The structure of 1 was determined as (3R(*), 3aS(*), 4S(*), 8aR(*))-3-(1'-hydroxy-1'-methylethyl)-5,8a-dimethyldecahydroazulen-4-ol by the combination of NMR and ESI-MS analyses.

Natural Products and Biological Activity of the Pharmacologically Active Cauliflower Mushroom Sparassis crispa

Sparassis crispa, also known as cauliflower mushroom, is an edible mushroom with medicinal properties. Its cultivation became popular in Japan about 10 years ago, a phenomenon that has been attributed not only to the quality of its taste, but also to its potential for therapeutic applications. Herein, I present a comprehensive summary of the pharmacological activities and mechanisms of action o...

Novel bioactive compound from the Sparassis crispa mushroom.

A novel compound (2) and a known one (1) were isolated from the mushroom, Sparassis crispa. Both compounds inhibited melanin synthesis and MRSA growth.

Generation and Evaluation of High β-Glucan Producing Mutant Strains of Sparassis crispa

A chemical mutagenesis technique was employed for development of mutant strains of Sparassis crispa targeting the shortened cultivation time and the high β-glucan content. The homogenized mycelial fragments of S. crispa IUM4010 strain were treated with 0.2 vol% methyl methanesulfonate, an alkylating agent, yielding 199 mutant strains. Subsequent screening in terms of growth and β-glucan content...

Tlc-bioautography: a Fast Method for Screening Biological Activities of Wild Mushrooms Extracts